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Asthmais a common infection that has a multifactorial origin including bothgenomic and ecological factors. According to Lloyd &amp Saglani(2013), allergic ailments have become prevalent and a primary sourceof infirmity in the unindustrialized countries. However, ecologicalmechanisms offer a real prospect of disease prevention while thedisentanglement of asthmatic genetic structure changes its taxonomyand action. Evidence has shown a significant correlation betweenvarious genetic components and susceptibility to asthma infection(March, Sleimam &amp Hakonarson, 2013).

Ann,a 13-year-old Caucasian girl with a protracted standing antiquity ofpoorly controlled asthma, was referred to HillTex clinic for apediatric pulmonic clinic assessment. She reported suffering fromtenacious wheezing, dyspnea, and difficulty in breathing. Moreover,cyclical allergies, workout, and virus-related illness were knownprompts of the acknowledged signs while nocturnal cough and pantingwere less frequent during the night. Ann was receiving two regulardosages of albuterol as rescue relievers for her asthmatic symptoms.A low dosage of inhaled corticosteroid integrated with beta agonistwas also recommended by her primary health care physician. Besides,Ann lived in a straw and hay farm with both her parents helping indaily activities within the farm. Her father was also an activesmoker though denied ever smoldering near children. Ann also revealedhaving a dog with unstable fur as her indoor pet hence high prospectof scattering the hair around people and the house. The familyaccount was also affirmative from asthma and cyclical allergies.

Asthmadisplays a stout genetic constituent that trails various means ofinheritance (Fereiraetal, 2014) Moreover, the intensifyinginclinations and significant disease pervasiveness have beenattributed to the environmental variations that have exposed thepre-existing vulnerability including locally operational factors.Exposure to various environmental pollutants such as tobacco smokeand other air pollutants, and exposure to potent oxidant stimuli arehighly associated with asthma. Alternatively, individuals having ahigh asthmatic load may be genetically susceptible to the standardsof environmental hygiene. Thus, asthma can result from environmentalas well as genetic factors (Wong, 2013)


Ferreira,M. A., Matheson, M. C., Tang, C. S., Granell,R., Ang, W., Hui, J., … &amp Bui, M. (2014). Genome-wideassociation analysis identifies 11 risk variants associated with theasthma with hay fever phenotype.Journalof Allergy and Clinical Immunology,133(6), 1564-1571.

Lloyd,C. M., &amp Saglani, S. (2013). Tcells in asthma: influences of genetics, environment, and T-cellplasticity.Journalof Allergy and Clinical Immunology,131(5),1267-1274.

March,M. E., Sleiman, P. M., &amp Hakonarson, H.(2013). Genetic polymorphisms and associated susceptibility toasthma. IntJ Gen Med,6(253),65.

Wong,W. M. (2013, November). ImpactOf Asthma Disease Management Program On Overall ControlAnd Quality of Life of Asthma Patients. In Respirology(Vol. 18, Pp. 152-152).